That Deus Ex is all I refer to when I think of how 2077 might turn out. In DE: MD, the level/quest options were just threefold? If I remember correctly: Kill everything, stealth about, or hack/bit of both? I can't see 2077 being much different...
I really, honestly worry about the statements from Miles Tost when he says stuff like perks will unlock different dialogue trees (how many perks are there!), your characters look will mean certain characters will react differently to you, your characters background that's created at the start of the game will lead to affiliations with similar 'classes' (grew up on the streets? Hoodrats will like you. Corporate? Suits will warm to you, etc).
I just cannot see how this much branching is possible. So much time and effort spent on stuff people will never see? You can only have so many CGI cut scenes....can you really have 20+ different endings?
But then again, they had what...250 staff for developing Witcher 3 and now there's nearly 900. So maybe they can.